The signs of negaim are two which, in fact, are four. The bright spot (baheret) is bright white like snow; secondary to it is the sign as white as the lime of the Temple. The rising (se'et) is as white of the skin of an egg; secondary to it is the like white wool, the words of Rabbi Meir. But the sages say: the rising (se'et) is white wool and secondary to it is like the white of the skin of an egg.

The variegation of the snow-like whiteness is like wine mixed with snow. The variegation of the lime-like whiteness is like blood mixed with milk, the words of Rabbi Ishmael. Rabbi Akiva says: the reddishness in either of them is like wine mixed with water, only that in the snow-like whiteness the color is bright while in that of lime-like whiteness it is duller.

These four colors combine with each other to declare free [from uncleanness], to certify or to shut up. "To shut up" one who is at the end of the first week; "To declare free [from uncleanness]", one who is at the end of the second week. "To certify", one in which a discoloration or white hair arose, by the end of the first week, by the end of the second week or after it had been declared free [from uncleanness]. "To certify", when a spreading arose in it by the end of the first week, by the end of the second week or after it had been declared free [from uncleanness]. "To certify", when all one's skin turned white after it had been declared free from uncleanness; "To declare free from uncleanness’, when all one's skin turned white after the sign had been certified unclean or after it had been shut up. These are the colors of signs of negaim upon which depend all decisions concerning negaim.

Rabbi Hanina, the vice-chief of priests, says: the colors of negaim are sixteen. Rabbi Dosa ben Harkinas says: the colors of negaim are thirty-six. Akaviah ben Mahalalel says: seventy-two. Rabbi Hanina the vice-chief of priests says: negaim may not be inspected for the first time at the end of Shabbat, since the end of that week will fall on Shabbat; Nor on a Monday, since the end of the second week will fall on Shabbat; Nor on a Tuesday, in the case of houses, since the end of the third week will fall on Shabbat. Rabbi Akiva says: they may be inspected at all times, and if the time for the second inspection falls on Shabbat it is postponed to after Shabbat; and this procedure leads sometimes to a leniency and sometimes to a stringency.

How does it lead to a leniency?If the nega had two white hairs and one white hair disappeared. If there were two white hairs and they turned black. If one hair was white and the other black and both turned black. If they were long and then they became short. If one was long and the other short and both became short. If a boil adjoined both hairs or one of them. If the boil surrounded both hairs or one of them. Or if they were separated from each other by a boil, the quick flesh of a boil, a burning, or the quick flesh of a burning, or a white scurf. If it had undiscolored flesh and this undiscolored flesh disappeared. If it was square and then became round or elongated. If it was encompassed and then moved to the side. If it was united and then it was dispersed. Or a boil appeared and made its way into it. If it was encompassed, parted or lessened by a boil, the quick flesh of a boil, a burning, the quick flesh of a burning, or a white scurf; If it had a spreading and then the spreading disappeared; Or the first sign itself disappeared or was so lessened that both are less than the size of a split bean; Or if a boil, the quick flesh of a boil, a burning, the quick flesh of a burning, or a white scurf, formed a division between the first sign and the spreading Behold these lead to a leniency in the law.